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A firearm anyone can download and print in their own home may be the most controversial application yet of consumer 3D printing. But some gunlovers, it seems, want to see it happen badly enough to put their wallets behind it.
This week, the so-called Wiki Weapon Project, an initiative that aims to design and build the world's first entirely 3D-printable handgun, met its goal of raising $20,000 from Internet donors, according to the group's spokesperson, University of Texas law student Cody Wilson. That's about ten times the amount the project had managed to raise through the crowdsourced fundraising site Indiegogo when the donation platform summarily booted the printable gun project from its website last month and refunded the group's pool of contributions to donors.
Water is 800% more dense than air, so unlike a bullet fired above the surface, once the bullet hits the water it immediately begins slowing down, the Science Channel explains. And instead of barreling towards Wahl, the bullet slows and falls to the bottom of the pool.
Decreasing dietary linoleic acid by up to 90% was not significantly correlated with changes in arachidonic acid levels in the phospholipid pool of plasma/serum (p = 0.39). Similarly, when dietary linoleic acid levels were increased up to six fold, no significant correlations with arachidonic acid levels were observed (p = 0.72). However, there was a positive relationship between dietary gamma-linolenic acid and dietary arachidonic acid on changes in arachidonic levels in plasma/serum phospholipids.
This study was designed to explore the relationship of dietary LA and tissue AA, viz., phospholipid pools of plasma/serum and erythrocytes. To our knowledge, this is the first study to review the literature as to whether increasing dietary LA is positively correlated with increasing tissue AA content, and whether reducing dietary LA has the opposite effect in adults consuming Western-type diets. We further investigated what potential contributions other dietary n-6 PUFA may have on tissue AA content. This study was limited in scope and did not address other controversial issues related to dietary LA or other PUFA or their effects on issues related to health.
The aim of this paper was to identify, review, and evaluate all peer-reviewed published literature presenting data outlining changes in dietary LA in adult human clinical trials which report phospholipid fatty acid composition (specifically AA) in plasma/serum and erythrocytes. We chose the phospholipid pool in plasma/serum because here is where a majority of the human data is, it represents membranes of lipoproteins derived from the surface of hepatic endoplasmic reticulum  (it helps to control for potential variations in other components, such as circulating triglycerides). The studies reporting the fatty acid composition of erythrocyte phospholipids do so because fatty acids in erythrocytes are almost totally esterified in phospholipids. Further refinements to the search strategy included reported changes in tissue AA levels following dietary intake of AA and its various n-6 PUFA precursors, i.e., LA and GLA. Published articles meeting eligibility criteria from 1970 to present were reviewed, of which 4336 articles were retrieved from May 2009 - November 2009 (Figure 1). The primary search engine used was PubMed.gov (The National Library of Medicine, National Institutes of Health), along with several prominent nutrition-based clinical journals, i.e., American Journal of Clinical Nutrition, British Journal of Nutrition, and any additional citations in articles reviewed. The search terms included linoleic acid, γ-linolenic acid, gamma-linolenic acid, arachidonic acid, omega-6, n-6, olive oil, soybean oil, sunflower oil, safflower oil, corn oil, omega-3, n-3, plasma, erythrocyte, red blood cell and phospholipid.
As observed from the distribution of the responses, there was wide variability. Some papers showed small increases in tissue AA levels when dietary LA changed, while other papers showed small decreases, but most of these changes lacked significance. When there was significance, the changes were minimal and the distribution pattern of the data did not favor an increase or a decrease. We chose plasma/serum and erythrocytes as the tissues of choice because here is where the bulk of data exists in the human literature. Erythrocytes represent a more stable pool of dietary lipids, contain very little neutral lipids and thus represents a membrane fraction of AA. Fasting plasma/serum phospholipid levels primarily (but not exclusively) represents in part phospholipids of lipoproteins that are derived from hepatic endoplasmic reticulum , and this pool is more responsive to more recent dietary PUFA intakes. 2b1af7f3a8